An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.

Arylamine N-acetyltransferases (NATs) catalyse the acetylation of arylamine, arylhydrazine and arylhydroxylamine substrates by acetyl Coenzyme A. NAT has been discovered in a wide range of eukaryotic and prokaryotic species. Although prokaryotic NATs have been implicated in xenobiotic metabolism, to...

書誌詳細
主要な著者:	Brooke, E, Davies, S, Mulvaney, A, Pompeo, F, Sim, E, Vickers, R
フォーマット:	Journal article
言語:	English
出版事項:	2003

類似資料

Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs).
著者:: Brooke, E, 等
出版事項: (2003)

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.
著者:: Westwood, I, 等
出版事項: (2010)

Structure and mechanism of arylamine N-acetyltransferases.
著者:: Westwood, I, 等
出版事項: (2006)

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding
著者:: Laurieri, N, 等
出版事項: (2014)

Structural Studies on the Mycobacterial Arylamine N-Acetyltransferases
著者:: Abuhammad, A, 等
出版事項: (2010)

Arylamine N-acetyltransferase in adult mouse brain
著者:: Mo, M, 等
出版事項: (2004)

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening.
著者:: Kawamura, A, 等
出版事項: (2005)

Neuroendocrine expression of mouse arylamine N-acetyltransferase 2
著者:: Wakefield, L, 等
出版事項: (2006)

Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
著者:: Sim, E, 等
出版事項: (2008)

Protein-ligand interactions of arylamine N-acetyltransferase from Mycobacterium smegmatis
著者:: Brooke, E
出版事項: (2003)

Hamster arylamine N-acetyltransferase 2: Investigation of substrate specificity by high-through-put screening
著者:: Kawamura, A, 等
出版事項: (2004)

Mapping the genes for arylamine N-acetyltransferases
著者:: Fakis, G
出版事項: (2000)

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.
著者:: Russell, A, 等
出版事項: (2009)

Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening.
著者:: Westwood, I, 等
出版事項: (2011)

Structural investigation of mutant Mycobacterium smegmatis arylamine N-acetyltransferase: a model for a naturally occurring functional polymorphism in Mycobacterium tuberculosis arylamine N-acetyltransferase.
著者:: Kawamura, A, 等
出版事項: (2003)

Arylamine N-acetyltransferase expression during murine heart development
著者:: Wakefield, L, 等
出版事項: (2004)

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site.
著者:: Abuhammad, A, 等
出版事項: (2010)

Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
著者:: Fullam, E, 等
出版事項: (2009)

Expression of the genes for arylamine N-acetyltransferases in mice
著者:: Boukouvala, S, 等
出版事項: (2002)

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.
著者:: Madikane, V, 等
出版事項: (2007)

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris
著者:: Madikane, V, 等
出版事項: (2007)

Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.
著者:: Wang, H, 等
出版事項: (2005)

Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG.
著者:: Anderton, M, 等
出版事項: (2006)

Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population
著者:: Hiba Chelouti, 等
出版事項: (2017-08-01)

Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus
著者:: Xinning Liu, 等
出版事項: (2021-01-01)

Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
著者:: Fullam, E, 等
出版事項: (2013)

Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
著者:: Fullam, E, 等
出版事項: (2013)

Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer
著者:: Amjad Mahasneh, 等
出版事項: (2012-01-01)

Arylamine N-Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status
著者:: Raúl A. Salazar-González, 等
出版事項: (2022-01-01)

Characterization of the putative operon containing arylamine N−acetyltransferase (nat) in Mycobacterium bovis BCG
著者:: Eltis, E
出版事項: (2006)

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages
著者:: Abuhammad, A, 等
出版事項: (2012)

Distribution of arylamine N-acetyltransferase 2 (NAT2) genotypes among Omanis
著者:: Musbah O. M. Tanira, 等
出版事項: (2003-04-01)

Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes
著者:: Christelle Vangenot, 等
出版事項: (2019-07-01)

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid.
著者:: Sandy, J, 等
出版事項: (2002)

Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker.
著者:: Laurieri, N, 等
出版事項: (2010)

A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1
著者:: Laurieri, N, 等
出版事項: (2013)

Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes
著者:: Mark A. Doll, 等
出版事項: (2017-07-01)

Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.
著者:: Adam, P, 等
出版事項: (2003)

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
著者:: Areej Abuhammad, 等
出版事項: (2012-01-01)

Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system.
著者:: Wakefield, L, 等
出版事項: (2008)