PPAR-gamma expression in pituitary tumours and the functional activity of the glitazones: evidence that any anti-proliferative effect of the glitazones is independent of the PPAR-gamma receptor.

OBJECTIVE: It has been reported that both normal pituitary and pituitary tumours express PPAR-gamma, a nuclear hormone receptor, the expression being more abundant in pituitary tumours, and that this is the basis for the reported antiproliferative effects of the thiazolidinedione, rosiglitazone, in...

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Bibliographic Details
Main Authors: Emery, M, Leontiou, C, Bonner, SE, Merulli, C, Nanzer, A, Musat, M, Galloway, M, Powell, M, Nikookam, K, Korbonits, M, Grossman, AB
Format: Journal article
Language:English
Published: 2006