A genome-wide association study on copy-number variation identifies a 11q11 loss as a candidate susceptibility variant for colorectal cancer.

Colorectal cancer (CRC) is a complex disease, and therefore its development is determined by the combination of both environmental factors and genetic variants. Although genome-wide association studies (GWAS) of SNP variation have conveniently identified 20 genetic variants so far, a significant pro...

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Библиографические подробности
Главные авторы: Fernandez-Rozadilla, C, Cazier, J, Tomlinson, I, Brea-Fernández, A, Lamas, M, Baiget, M, López-Fernández, L, Clofent, J, Bujanda, L, Gonzalez, D, de Castro, L, Hemminki, K, Bessa, X, Andreu, M, Jover, R, Xicola, R, Llor, X, Moreno, V, Castells, A, Castellví-Bel, S, Carracedo, A, Ruiz-Ponte, C
Формат: Journal article
Язык:English
Опубликовано: 2014