Plasmodium falciparum PHIST proteins contribute to cytoadherence and anchor PfEMP1 to the host cell cytoskeleton
Adherence of <em>Plasmodium falciparum</em> infected erythrocytes to host endothelium is conferred through the parasite-derived virulence factor PfEMP1, the major contributor to malaria severity. PfEMP1 located at knob structures on the erythrocyte surface is anchored to the cytoskeleton...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Published: |
John Wiley & Sons Ltd
2016
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