Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice
Most current analysis tools for antibody next-generation sequencing data work with primary sequence descriptors, leaving accompanying structural information unharnessed. We have used novel rapid methods to structurally characterize the complementary-determining regions (CDRs) of more than 180 millio...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2020
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