Invasive potential of human rheumatoid tenosynovial cells is in part MT1-MMP dependent.

PURPOSE: In rheumatoid arthritis, tenosynovial invasion of tendon is associated with an increased rate of tendon rupture and a worse clinical prognosis compared to noninvasive disease. Tendon is composed predominantly of type I collagen, which can be efficiently degraded by collagenolytic matrix met...

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Bibliographic Details
Main Authors: Jain, A, Miller, M, Troeberg, L, Itoh, Y, Brennan, F, Nanchahal, J
Format: Journal article
Language:English
Published: 2009