Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS

OBJECTIVE: Neurofilaments are leading neurochemical biomarkers for amyotrophic lateral sclerosis (ALS). Here, we investigated the effect of preanalytical factors on neurofilament concentrations in cerebrospinal fluid (CSF) in a “reverse” round-robin with 15 centers across Europe/U.S. METHODS: Sample...

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Bibliographic Details
Main Authors: Oeckl, P, Jardel, C, Salachas, F, Lamari, F, Andersen, P, Bowser, R, de Carvalho, M, Costa, J, van Damme, P, Gray, E, Grosskreutz, J, Hernández-Barral, M, Herukka, S, Huss, A, Jeromin, A, Kirby, J, Kuzma-Kozakiewicz, M, Amador, M, Mora, J, Morelli, C, Muckova, P, Petri, S, Poesen, K, Rhode, H, Rikardsson, A, Robberecht, W, Rodríguez Mahillo, A, Shaw, P, Silani, V, Steinacker, P, Turner, M, Tüzün, E, Yetimler, B, Ludolph, A, Otto, M
Format: Journal article
Published: Taylor and Francis 2016