Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen.

The weakness in myasthenia gravis (MG) is mediated by autoantibodies against adult muscle acetylcholine receptors (AChR) at the neuromuscular junction; most of these antibodies also bind to fetal AChR, which is present in the thymus. In rare cases, babies of mothers with MG, or even of asymptomatic...

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Hlavní autoři: Matthews, I, Sims, G, Ledwidge, S, Stott, D, Beeson, D, Willcox, N, Vincent, A
Médium: Journal article
Jazyk:English
Vydáno: 2002