Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection
The Zika virus (ZIKV) epidemic has resulted in congenital abnormalities in fetuses and neonates. Although some cross-reactive dengue virus (DENV)-specific antibodies can enhance ZIKV infection in mice, those recognizing the DENV E-dimer epitope (EDE) can neutralize ZIKV infection in cell culture. We...
主要な著者: | , , , , , , , , , , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
Springer Nature
2017
|