HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently.

The ability of HIV-1-specific CD8(+) T cell responses to recognize epitope variants resulting from viral sequence variation in vivo may affect the ease with which HIV-1 can escape T cell control and impact on the rate of disease progression in HIV-1-infected humans. Here, we studied the functional c...

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Bibliographic Details
Main Authors: Turnbull, E, Lopes, A, Jones, N, Cornforth, D, Newton, P, Aldam, D, Pellegrino, P, Turner, J, Williams, I, Wilson, C, Goepfert, P, Maini, M, Borrow, P
Format: Journal article
Language:English
Published: 2006