Synthesis of stereoisomers of Artemisia and Chrysanthemum bis(acetylenic) enol ether spiroacetals.
An 11-step synthesis is described of two diastereomeric candidates for a bis(acetylenic) enol ether spiroacetal isolated from Chrysanthemum boreale. Key steps in the synthetic route include spiroacetal lactone alkylidenation and subseqent modified Cadiot-Chodkiewicz cross-coupling to install the bis...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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