A systems biology approach to define SARS-CoV-2 correlates of protection in non-human primates

A systems biology approach to define SARS-CoV-2 correlates of protection in non-human primates

SARS-CoV-2 is expected to become a seasonal human coronavirus, with annual vaccination advised for vulnerable populations, similar to influenza. Unlike influenza, correlates of protection (CoPs) for SARS-CoV-2 have yet to be defined, which will impede the approval of new vaccines. Here, we present t...

Deskribapen osoa

Xehetasun bibliografikoak
Egile nagusia:	Brady, C
Beste egile batzuk:	Carroll, M
Formatua:	Thesis
Hizkuntza:	English
Argitaratua:	2024
Gaiak:	Systems biology Vaccinology Immunology

Antzeko izenburuak

Evaluation of the immunogenicity of a promising vaccine regimen to identify immune correlates of protection
nork: Pinpathomrat, N
Argitaratua: (2018)

Towards a universally effective HLA-E-targeted HIV vaccine - a structural and biophysical exploration
nork: Walters, L
Argitaratua: (2019)

Evaluation of immune correlates to TB vaccines
nork: Marsay, L
Argitaratua: (2011)

Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
nork: Ronan, E
Argitaratua: (2011)

Understanding the link between interleukin 17 and vaccine-induced protection in tuberculosis
nork: Griffiths, K
Argitaratua: (2012)

The role of lung tissue-resident memory T cells in protection against tuberculosis
nork: Bull, N
Argitaratua: (2017)

Effect of needle size on immunogenicity and reactogenicity of vaccines in infants: randomised controlled trial
nork: Diggle, L, et al.
Argitaratua: (2006)

Comparison of a limiting dilution assay and ELISpot for detection of memory B-cells before and after immunisation with a protein-polysaccharide conjugate vaccine in children
nork: Blanchard-Rohner, G, et al.
Argitaratua: (2010)

Biodegradable pulsatile release technologies for viral vector based vaccinations
nork: Krastev, C
Argitaratua: (2018)

The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM197 conjugate vaccine
nork: Clutterbuck, E, et al.
Argitaratua: (2006)

SARS-CoV-2 mRNA Dual Immunization Induces Innate Transcriptional Signatures, Establishes T-Cell Memory and Coordinates the Recall Response
nork: Ioanna Papadatou, et al.
Argitaratua: (2023-01-01)

Nonhuman primate antigenic cartography of SARS-CoV-2
nork: Annika Rössler, et al.
Argitaratua: (2025-01-01)

Design and Immune Profile of Multi-Epitope Synthetic Antigen Vaccine Against SARS-CoV-2: An In Silico and In Vivo Approach
nork: Maria da Conceição Viana Invenção, et al.
Argitaratua: (2025-01-01)

Development of an ancestral DC and TLR4-inducing multi-epitope peptide vaccine against the spike protein of SARS-CoV and SARS-CoV-2 using the advanced immunoinformatics approaches
nork: Cena Aram, et al.
Argitaratua: (2024-09-01)

Of mice and MenB: assessing the immune mechanisms underlying meningococcal capsular group B vaccines in mice
nork: Sheerin, D
Argitaratua: (2019)

Innate immune pathways controlling IL-1beta production and adjuvant-induced T helper 17 cell differentiation
nork: Shenderov, K
Argitaratua: (2011)

Development of antimalarial human monoclonal antibodies against Plasmodium falciparum
nork: Wang, LT
Argitaratua: (2022)

Towards the development of multi-disease vaccines against arthropod-borne viruses
nork: Montalvo Zurbía Flores, G
Argitaratua: (2022)

A simplified 4-site economical intradermal post-exposure rabies vaccine regimen: a randomised controlled comparison with standard methods
nork: Warrell, M, et al.
Argitaratua: (2008)

A reverse vaccinology approach to the identification and characterization of Ctenocephalides felis candidate protective antigens for the control of cat flea infestations
nork: Marinela Contreras, et al.
Argitaratua: (2018-01-01)

Long term efficacy of a pre-erythrocytic malaria vaccine and correlates of protection in children residing in a malaria endemic country
nork: Olotu, A
Argitaratua: (2013)

SARS-CoV-2 leverages airway epithelial protective mechanism for viral infection
nork: Allison Marie Greaney, et al.
Argitaratua: (2023-03-01)

mRNA-1273 vaccination protects against SARS-CoV-2–elicited lung inflammation in nonhuman primates
nork: Adam T. Waickman, et al.
Argitaratua: (2022-07-01)

Towards improved blood-stage malaria vaccines: characterising the underlying immunogenicity of vaccine adjuvants and vectors
nork: de Cassan, S
Argitaratua: (2011)

Exploiting pre-existing viral immunity for B cell vaccination against endogenous antigens
nork: Wong, S
Argitaratua: (2013)

B cell responses to conjugate and polysaccharide meningococcal vaccines
nork: Ramasamy, M
Argitaratua: (2012)

The role of antigen in the maintenance and localisation of CD8+ T-cells in the context of liver stage malaria
nork: Gola, A
Argitaratua: (2018)

Malaria pre-erythrocytic stage vaccines: targeting antigen combinations
nork: Bauza, K
Argitaratua: (2012)

New approaches for improving the immunogenicity of modified vaccinia virus Ankara as a recombinant vaccine vector
nork: Alharbi, N
Argitaratua: (2014)

Quantum vaccinomics platforms to advance in vaccinology
nork: José de la Fuente, et al.
Argitaratua: (2023-06-01)

Mitochondria: In the Cross Fire of SARS-CoV-2 and Immunity
nork: Johannes Burtscher, et al.
Argitaratua: (2020-10-01)

Control of typhoid fever: evaluating herd protection through public health use of typhoid VI polysaccharide vaccine
nork: Ochiai, R
Argitaratua: (2011)

COH04S1 and beta sequence-modified vaccine protect hamsters from SARS-CoV-2 variants
nork: Felix Wussow, et al.
Argitaratua: (2022-06-01)

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
nork: Matsumiya, M, et al.
Argitaratua: (2014)

Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates
nork: Antoni Prenafeta, et al.
Argitaratua: (2023-07-01)

Variant- and vaccination-specific alternative splicing profiles in SARS-CoV-2 infections
nork: Sung-Gwon Lee, et al.
Argitaratua: (2024-03-01)

Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection
nork: Marie Alexandre, et al.
Argitaratua: (2022-07-01)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination
nork: Harris, S, et al.
Argitaratua: (2013)

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
nork: Hennig, B, et al.
Argitaratua: (2008)

Influence of genetic and environmental factors on the immunogenicity of Hib vaccine in Gambian twins
nork: Lee, Y, et al.
Argitaratua: (2006)