Lck and the nature of the T cell receptor trigger.
Exactly how ligand binding 'triggers' T cell receptor (TCR) phosphorylation is unclear. It has been proposed that ligand engagement by the TCR somehow activates the Src kinase Lck, which in turn phosphorylates the receptor. Recent data, however, suggest instead that a significant fraction...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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