Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.

The reaction of enol(ate)s with electrophiles is used extensively in organic synthesis for stereoselective C-C bond formation. Protein-based catalysts have had comparatively limited application for the stereoselective formation of C-C bonds of choice via enolate chemistry. We describe protein engine...

书目详细资料
Main Authors:	Hamed, R, Gomez-Castellanos, JR, Thalhammer, A, Harding, D, Ducho, C, Claridge, T, Schofield, C
格式:	Journal article
语言:	English
出版:	2011

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