Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.
The reaction of enol(ate)s with electrophiles is used extensively in organic synthesis for stereoselective C-C bond formation. Protein-based catalysts have had comparatively limited application for the stereoselective formation of C-C bonds of choice via enolate chemistry. We describe protein engine...
المؤلفون الرئيسيون: | , , , , , , |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2011
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