The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells.

The interaction between a T cell and an antigen-presenting cell (APC) can trigger a signaling response that leads to T cell activation. Prior studies have shown that ligation of the T cell receptor (TCR) triggers a signaling cascade that proceeds through the coalescence of TCR and various signaling...

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Bibliographic Details
Main Authors: Kaizuka, Y, Douglass, A, Vardhana, S, Dustin, M, Vale, R
Format: Journal article
Language:English
Published: 2009