Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression.

To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto-Kakizaki (GK) rats and Brown-Norway (BN) controls, which contain well-defined bloc...

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Bibliographic Details
Main Authors: Kaisaki, P, Otto, G, Argoud, K, Collins, S, Wallis, R, Wilder, S, Yau, A, Hue, C, Calderari, S, Bihoreau, M, Cazier, J, Mott, R, Gauguier, D
Format: Journal article
Language:English
Published: Genetics Society of America 2016