The interstitial response to renal injury: fibroblast-like cells show phenotypic changes and have reduced potential for erythropoietin gene expression.

To define the potential for erythropoietin gene expression in injured kidneys, marker gene expression was examined in transgenic mice bearing a homologously recombined erythropoietin--simian virus 40 T antigen (Epo-TAg) transgene. Three types of renal injury were studied: ureteric obstruction, globa...

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Bibliographic Details
Main Authors: Maxwell, P, Ferguson, D, Nicholls, L, Johnson, M, Ratcliffe, P
Format: Journal article
Language:English
Published: 1997