Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11.

A young onset of type 2 diabetes is likely to result, in part, from greater genetic susceptibility. Young-onset families may therefore represent a group in which genes are more easily detectable by linkage. To test this hypothesis, we conducted age at diagnosis (AAD) stratified linkage analyses in t...

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Bibliographic Details
Main Authors: Frayling, T, Wiltshire, S, Hitman, G, Walker, M, Levy, J, Sampson, M, Groves, C, Menzel, S, McCarthy, M, Hattersley, A
Format: Journal article
Language:English
Published: 2003