Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells.
In humans, polyadenylation of messenger RNA (mRNA) protects transcripts from degradation and enhances translation efficiency. Conversely, in bacteria, polyadenylation destabilizes mRNA. RNA adenylation was recently implicated in promoting degradation of some yeast RNAs by the exosome. The exosome co...
主要な著者: | , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2006
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