Pyocin S5 import into Pseudomonas aeruginosa reveals a generic mode of bacteriocin transport

Pyocin S5 (PyoS5) is a potent protein bacteriocin that eradicates the human pathogen Pseudomonas aeruginosa in animal infection models, but its import mechanism is poorly understood. Here, using crystallography, biophysical and biochemical analyses, and live-cell imaging, we define the entry process...

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Bibliographic Details
Main Authors: Behrens, HM, Lowe, ED, Gault, J, Housden, NG, Kaminska, R, Weber, TM, Thompson, CMA, Mislin, GLA, Schalk, IJ, Walker, D, Robinson, CV, Kleanthous, C
Format: Journal article
Language:English
Published: American Society for Microbiology 2020