Single-nucleotide polymorphisms in the p53 signaling pathway.
The p53 tumor suppressor pathway is central both in reducing cancer frequency in vertebrates and in mediating the response of commonly used cancer therapies. This article aims to summarize and discuss a large body of evidence suggesting that the p53 pathway harbors functional inherited single-nucleo...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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