Effect of inhibitors of oxidative phosphorylation on erythropoietin mRNA in isolated perfused rat kidneys.

We have used RNase protection to measure oxygen-dependent changes in erythropoietin (EPO) mRNA in isolated perfused kidneys and to compare the effect of hypoxia with the response to inhibitors of oxidative phosphorylation. In well-oxygenated kidneys perfused for 2 h at 12 ml/min, with hematocrit of...

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Bibliographic Details
Main Authors: Tan, C, Ratcliffe, P
Format: Journal article
Language:English
Published: 1991