Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution

Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution

The steps in the progression from subclinical clonal haemopoiesis to acute myeloid leukaemia (AML) have not been defined, nor has its likelihood or latency. NPM1 mutations were not found to drive clonal haemopoiesis in haematologically normal individuals(Genovese et al, 2014; Jaiswal et al, 2014; Xi...

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Bibliografiske detaljer
Main Authors:	Grove, C, Bolli, N, Manes, N, Varela, I, Van't Veer, M, Bench, A, Eldaly, H, Wedge, D, Van Loo, P, Vassiliou, G
Format:	Journal article
Udgivet:	Wiley 2016

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af: Karamitros, D, et al.
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af: Boultwood, J, et al.
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Secondary acute myeloid leukaemia in children treated for acute lymphoblastic leukaemia.
af: Eden, O, et al.
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af: Guinn, B, et al.
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