The role of the priming loop in influenza A virus RNA synthesis

The role of the priming loop in influenza A virus RNA synthesis

RNA-dependent RNA polymerases (RdRps) are used by RNA viruses to replicate and transcribe their RNA genomes1 . They adopt a closed, right-handed fold with conserved subdomains called palm, fingers and thumb1,2. Conserved RdRp motifs A–F coordinate the viral RNA template, NTPs and magnesium ions to f...

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Autors principals:	Te Velthuis, A, Robb, N, Kapanidis, A, Fodor, E
Format:	Journal article
Publicat:	Nature 2016

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