Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapy.
Blockade of CD40-CD154 interactions can facilitate long-term allograft acceptance in selected rodent and in primate models, but, due to the ability of CD154-independent CD8(+) T cells to initiate graft rejection, this strategy is not always effective. In this work we demonstrate that blockade of the...
Hlavní autoři: | van Maurik, A, Herber, M, Wood, K, Jones, N |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2002
|
Podobné jednotky
-
Dependency of direct pathway CD4+ T cells on CD40-CD154 costimulation is determined by nature and microenvironment of primary contact with alloantigen.
Autor: van Maurik, A, a další
Vydáno: (2004) -
Regulation of transplant arteriosclerosis by CD25+CD4+ T cells generated to alloantigen in vivo.
Autor: Warnecke, G, a další
Vydáno: (2007) -
Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process.
Autor: Karim, M, a další
Vydáno: (2004) -
Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy.
Autor: Jorieke H Peters, a další
Vydáno: (2008-01-01) -
Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells.
Autor: Mottet, C, a další
Vydáno: (2003)