Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.

Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.

Ring closure of a 3,5-di-O-triflate derived from D-altrose with benzylamine allowed the formation of both monocyclic and bicyclic azetidine analogues of swainsonine.

Bibliographic Details
Main Authors: Araújo, N, Jenkinson, S, Martínez, R, Glawar, A, Wormald, M, Butters, T, Nakagawa, S, Adachi, I, Kato, A, Yoshihara, A, Akimitsu, K, Izumori, K, Fleet, G
Format: Journal article
Language:English
Published: 2012

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