Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells.

BACKGROUND: In a specialized epithelial cell such as the Drosophila photoreceptor, a conserved set of proteins is essential for the establishment of polarity, its maintenance, or both--in Drosophila, these proteins include the apical factors Bazooka, D-atypical protein kinase C, and D-Par6 together...

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Bibliographic Details
Main Authors: Pinal, N, Goberdhan, D, Collinson, L, Fujita, Y, Cox, I, Wilson, C, Pichaud, F
Format: Journal article
Language:English
Published: 2006