The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

T cells rely for their development and function on the correct folding and turnover of proteins generated in response to a broad range of molecular cues. In the absence of the eukaryotic type II chaperonin complex, CCT, T cell activation induced changes in the proteome are compromised including the...

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Dettagli Bibliografici
Autori principali:	Oftedal, BE, Maio, S, Handel, AE, White, MPJ, Howie, D, Davis, S, Prevot, N, Rota, IA, Deadman, ME, Kessler, BM, Fischer, R, Trede, NS, Sezgin, E, Maizels, RM, Holländer, GA
Natura:	Journal article
Lingua:	English
Pubblicazione:	Springer Nature 2021

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