Autoantibodies to glutamic acid decarboxylase in patients with epilepsy are associated with low cortical GABA levels.

Autoantibodies to glutamic acid decarboxylase in patients with epilepsy are associated with low cortical GABA levels.

Antibodies to glutamic acid decarboxylase (GAD), the major pathway for the synthesis of c-aminobutyric acid(GABA) in humans, are found at elevated levels in a subgroup of patients with chronic epilepsy. To test whether the antibodies were associated with changes in cortical GABA levels we used magne...

Bibliografiset tiedot
Päätekijät:	Stagg, C, Lang, B, Best, J, McKnight, K, Cavey, A, Johansen-Berg, H, Vincent, A, Palace, J
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2010

Samankaltaisia teoksia

SERUM AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE ARE ASSOCIATED WITH REDUCED CORTICAL GABA LEVELS IN PATIENTS WITH EPILEPSY
Tekijä: Stagg, C, et al.
Julkaistu: (2009)

The role of anti-glutamic acid decarboxylase autoantibodies (GAD-Ab) in idiopathic late onset cerebellar ataxia (ILOCA)
Tekijä: Muzaimi, M, et al.
Julkaistu: (2004)

Glutamic Acid Decarboxylase Autoantibodies-Related Encephalitis
Tekijä: J Gordon Millichap
Julkaistu: (2011-09-01)

Autoantibodies as a cause of epilepsy
Tekijä: Wroe, S, et al.
Julkaistu: (2003)

Serum antibodies in patients with epilepsy
Tekijä: Lang, B, et al.
Julkaistu: (2005)

Neuronal surface and glutamic acid decarboxylase autoantibodies in Nonparaneoplastic stiff person syndrome.
Tekijä: Chang, T, et al.
Julkaistu: (2013)

Role of glutamic acid decarboxylase 67 in regulating cortical parvalbumin and GABA membrane transporter 1 expression: Implications for schizophrenia
Tekijä: Allison A. Curley, et al.
Julkaistu: (2013-02-01)

Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias
Tekijä: Hiroshi Mitoma, et al.
Julkaistu: (2017-01-01)

Control of cortical neuronal migration by glutamate and GABA
Tekijä: Heiko J Luhmann, et al.
Julkaistu: (2015-01-01)

Estimation of Insulin and Glutamic Acid Decarboxylase Autoantibodies In Patients With Type 1 Diabetes Mellitus
Tekijä: Abbas J Mohammed
Julkaistu: (2019-06-01)

Estimation of Insulin and Glutamic Acid Decarboxylase Autoantibodies In Patients With Type 1 Diabetes Mellitus
Tekijä: Abbas J Mohammed
Julkaistu: (2019-06-01)

Glutamate Decarboxylase from Lactic Acid Bacteria—A Key Enzyme in GABA Synthesis
Tekijä: Ida Bagus Agung Yogeswara, et al.
Julkaistu: (2020-12-01)

Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission.
Tekijä: Chandana Buddhala, et al.
Julkaistu: (2012-01-01)

AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
Tekijä: N. V. Piven, et al.
Julkaistu: (2014-07-01)

Autoantibodies in epilepsy
Tekijä: Lang, B, et al.
Julkaistu: (2007)

Regulation of glutamic acid decarboxylase of chick and rat retina cells by GABA and excitatory amino acids
Tekijä: ALMEIDA OLGA MARIA M.S. DE, et al.
Julkaistu: (2000-01-01)

Relationship between physiological measures of excitability and levels of glutamate and GABA in the human motor cortex.
Tekijä: Stagg, C, et al.
Julkaistu: (2011)

Relationship between physiological measures of excitability and levels of glutamate and GABA in the human motor cortex
Tekijä: Stagg, C, et al.
Julkaistu: (2011)

α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals
Tekijä: Nicolai M. Doliba, et al.
Julkaistu: (2022-06-01)

Serum antibodies in epilepsy and seizure-associated disorders.
Tekijä: McKnight, K, et al.
Julkaistu: (2005)

New-onset focal epilepsy with palatal tremor and glutamic acid decarboxylase antibodies responding to intravenous immunoglobulin.
Tekijä: Marnane, M, et al.
Julkaistu: (2008)

Anti-glutamic acid decarboxylase limbic encephalitis without epilepsy evolving into dementia with cerebellar ataxia.
Tekijä: Mirabelli-Badenier, M, et al.
Julkaistu: (2012)

Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels.
Tekijä: Mariana Urrutia, et al.
Julkaistu: (2016-01-01)

Cerebellar ataxia associated with anti-glutamic acid decarboxylase (anti-GAD) autoantibodies: a rare and puzzling disease
Tekijä: Hélio A. G. Teive

The role of GABA in human motor learning.
Tekijä: Stagg, C, et al.
Julkaistu: (2011)

Relationship between the prevalence of anti-glutamic acid decarboxylase autoantibodies and duration of type 1 diabetes mellitus in Brazilian patients
Tekijä: M. Rodacki, et al.
Julkaistu: (2004-11-01)

The dynamics of cortical GABA in human motor learning
Tekijä: Kolasinski, J, et al.
Julkaistu: (2018)

Immunoprofiling of drug-resistant epilepsy with a focus on glutamic acid decarboxylase 65 antibodies
Tekijä: McGinty, R
Julkaistu: (2021)

The Incidence of Glutamic Acid Decarboxylase Autoantibodies and its Association With Clinical Features in Pregnant Women With Gestational Diabetes Mellitus
Tekijä: Malihe Mohammadi, et al.
Julkaistu: (2019-06-01)

Prefrontal cortical alterations of glutamate and GABA neurotransmission in schizophrenia: Insights for rational biomarker development
Tekijä: Kirsten E. Schoonover, et al.
Julkaistu: (2020-12-01)

What are we measuring with GABA magnetic resonance spectroscopy?
Tekijä: Stagg, C, et al.
Julkaistu: (2011)

Zinc transporter 8 autoantibodies complement glutamic acid decarboxylase and insulinoma‐associated antigen‐2 autoantibodies in the identification and characterization of Japanese type 1 diabetes
Tekijä: Eiji Kawasaki, et al.
Julkaistu: (2020-09-01)

Autoimmune musicogenic epilepsy associated with anti‐glutamic acid decarboxylase antibodies and Stiff‐person syndrome
Tekijä: Joana Jesus‐Ribeiro, et al.
Julkaistu: (2020-01-01)

UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes
Tekijä: Turner, R, et al.
Julkaistu: (1997)

Glucose control in UKPDS type 2 diabetic patients with and without autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase.
Tekijä: Mehta, Z, et al.
Julkaistu: (1999)

Cerebellar ataxia associated to anti-glutamic acid decarboxylase autoantibody (anti-GAD): partial improvement with intravenous immunoglobulin therapy
Tekijä: José Luiz Pedroso, et al.
Julkaistu: (2011-12-01)

Glutamic Acid Decarboxylase Autoantibody Detection by Electrochemiluminescence Assay Identifies Latent Autoimmune Diabetes in Adults with Poor Islet Function
Tekijä: Yuxiao Zhu, et al.
Julkaistu: (2020-04-01)

A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes
Tekijä: Alexandra Martin, et al.
Julkaistu: (2022-12-01)

A mean-field model of glutamate and GABA synaptic dynamics for functional MRS
Tekijä: Caroline A. Lea-Carnall, et al.
Julkaistu: (2023-02-01)

Other Significant Metabolites. Myo-Inositol, GABA, Glutamine, and Lactate.
Tekijä: Best, J, et al.
Julkaistu: (2013)