Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase.

Phytanoyl-CoA hydroxylase (PAHX) catalyzes an important step in the metabolism of the fatty acid side chain of chlorophyll. PHYHD1 exists in three isoforms and is the closest human homologue of PAHX. We show that like PAHX, the PHYHD1A but likely not the PHYHD1B/C isoforms, is a functional Fe(II) an...

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Bibliographic Details
Main Authors: Zhang, Z, Kochan, G, Ng, S, Kavanagh, K, Oppermann, U, Schofield, C, McDonough, M
Format: Journal article
Language:English
Published: 2011