DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation.
Dilated cardiomyopathy (DCM) can be caused by a Gly159Asp mutation in cardiac troponin C (cTnC). Our previous work found that partial replacement of endogenous troponin in skinned muscle fibres with human cardiac troponin containing Gly159Asp cTnC had no significant effect on maximum force generatio...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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