Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding.
Using a cytological assay to monitor the successive chromatin association of replication proteins leading to replication initiation, we have investigated the function of fission yeast Cdc23/Mcm10 in DNA replication. Inactivation of Cdc23 before replication initiation using tight degron mutations has...
Autors principals: | Gregan, J, Lindner, K, Brimage, L, Franklin, R, Namdar, M, Hart, E, Aves, S, Kearsey, S |
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Format: | Journal article |
Idioma: | English |
Publicat: |
2003
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