Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance

Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance

The mechanisms of endotoxin tolerance (ET), which down-regulate inflammation, are well described in response to exogenous toll-like receptor ligands, but few studies have focused on ET-associated mechanisms in inflammatory disease. As blocking TNF can attenuate the development of ET, the effect of a...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Taylor, PC, Clanchy, FIL, Borghese, F, Bystrom, J, Balog, A, Penn, H, Hull, DN, Williams, RO, Mageed, RA
Format: Journal article
Sprache:English
Veröffentlicht: Elsevier 2024

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