A novel three-dimensional culture system allows prolonged culture of functional human granulosa cells and mimics the ovarian environment.

The development of techniques allowing the growth of primordial follicles to mature follicles in vitro has much potential for both reproductive medicine and developmental research. However, human primordial and preantral follicles fail to grow after isolation from the surrounding ovarian stroma. Gra...

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Bibliographic Details
Main Authors: Kossowska-Tomaszczuk, K, Pelczar, P, Güven, S, Kowalski, J, Volpi, E, De Geyter, C, Scherberich, A
Format: Journal article
Language:English
Published: Mary Ann Liebert Inc. 2010