The effect of mutations in the lid region of Thermomyces lanuginosus lipase on interactions with triglyceride surfaces: a multi-scale simulation study

Lipases naturally function at the interface formed between amphiphilic molecules and the aqueous environment. Thermomyces lanuginosus lipase (TLL) is a well-characterised lipase, known to exhibit interfacial activation during which a lid region covering the active site becomes displaced upon interac...

Full description

Bibliographic Details
Main Authors: Willems, N, Lelimousin, M, Skjold-Jorgensen, J, Svendsen, A, Sansom, M
Format: Journal article
Published: Elsevier 2017