Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses.

CD8(+) T cells are critical for the control of many persistent viral infections, such as human immunodeficiency virus, hepatitis C virus, Epstein-Barr virus, and cytomegalovirus (CMV). In most infections, large CD8(+)-T-cell populations are induced early but then contract and are maintained thereaft...

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Bibliographic Details
Main Authors: Karrer, U, Wagner, M, Sierro, S, Oxenius, A, Hengel, H, Dumrese, T, Freigang, S, Koszinowski, U, Phillips, R, Klenerman, P
Format: Journal article
Language:English
Published: 2004