COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord.

BACKGROUND: While multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) are primarily inflammatory and degenerative disorders respectively, there is increasing evidence for shared cellular mechanisms that may affect disease progression, particularly glial responses. Cyclooxygenase 2 (COX-...

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Bibliographic Details
Main Authors: Yiangou, Y, Facer, P, Durrenberger, P, Chessell, I, Naylor, A, Bountra, C, Banati, R, Anand, P
Format: Journal article
Language:English
Published: 2006