Is nevirapine dose-escalation appropriate in young, African, HIV-infected children?

OBJECTIVES: Young children metabolize nevirapine faster than older children/adults. We evaluated nevirapine pharmacokinetics with or without dose-escalation in Zambian, HIV-infected infants/children and its relationship with safety/efficacy. DESIGN: A retrospective pharmacokinetic substudy of the CH...

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Bibliographic Details
Main Authors: Fillekes, Q, Mulenga, V, Kabamba, D, Kankasa, C, Thomason, M, Cook, A, Chintu, C, Gibb, D, Walker, A, Burger, D
Format: Journal article
Language:English
Published: 2013