A second-generation total synthesis of spirastrellolide A methyl ester.

Marine macrolides: an improved second-generation total synthesis of the anticancer macrolide spirastrellolide A methyl ester has been achieved. The synthesis features a uniformly high level of stereocontrol combined with more expedient fragment assembly, and demonstrates a critical dependence of the...

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Bibliographic Details
Main Authors: Paterson, I, Maltas, P, Dalby, S, Lim, J, Anderson, E
Format: Journal article
Language:English
Published: 2012