Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome.

Rett syndrome (RTT) is a severe form of mental retardation, which is caused by spontaneous mutations in the X-linked gene MECP2. How the loss of MeCP2 function leads to RTT is currently unknown. Mice lacking the Mecp2 gene initially show normal postnatal development but later acquire neurological ph...

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Bibliographic Details
Main Authors: Nuber, U, Kriaucionis, S, Roloff, T, Guy, J, Selfridge, J, Steinhoff, C, Schulz, R, Lipkowitz, B, Ropers, H, Holmes, M, Bird, A
Format: Journal article
Language:English
Published: 2005