Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca2+ release

Somatostatin secretion from pancreatic islet δ-cells is stimulated by elevated glucose levels, but the underlying mechanisms have only partially been elucidated. Here we show that glucose-induced somatostatin secretion (GISS) involves both membrane potential-dependent and -independent pathways. Alth...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Denwood, G, Tarasov, A, Salehi, A, Vergari, E, Ramracheya, R, Takahashi, H, Nikolaev, V, Seino, S, Gribble, F, Reimann, F, Rorsman, P, Zhang, Q
פורמט: Journal article
שפה:English
יצא לאור: Rockefeller University Press 2019