Th1 cytokines are upregulated by adenoviral vectors in the brains of primed mice.

A major disadvantage of first generation adenoviral vectors for gene therapy in the brain is the immune response they elicit. Human adenovirus is a common respiratory virus and earlier exposure to it has important implications for gene therapy. We show that the immune response against E1-deleted ade...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Lee, M, McMenamin, M, Byrnes, A, Charlton, H, Wood, M
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2008