Th1 cytokines are upregulated by adenoviral vectors in the brains of primed mice.
A major disadvantage of first generation adenoviral vectors for gene therapy in the brain is the immune response they elicit. Human adenovirus is a common respiratory virus and earlier exposure to it has important implications for gene therapy. We show that the immune response against E1-deleted ade...
Päätekijät: | , , , , |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2008
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