TNFα-induced macrophage chemokine secretion is more dependent on NF-κB expression than lipopolysaccharides-induced macrophage chemokine secretion

The transcription factor NF-κB is a pivotal intracellular regulator of many inflammatory responses and it has been proposed that it represents a potential therapeutic target. As chemokines are important for the progress of an inflammatory response by the recruitment of immuno-competent cells, the ro...

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Bibliographic Details
Main Authors: Ciesielski, C, Andreakos, E, Foxwell, B, Feldmann, M
Format: Journal article
Language:English
Published: 2002