Increased IgG4 responses to multiple food and animal antigens indicate a polyclonal expansion and differentiation of pre-existing B cells in IgG4-related disease
<strong>Background:</strong> IgG4-related disease (IgG4-RD) is a systemic fibroinflammatory condition, characterised by an elevated serum IgG4 concentration and abundant IgG4-positive plasma cells in the involved organs. An important question is whether the elevated IgG4 response is caus...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
BMJ Publishing Group
2015
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