Extracellular matrix protein-1 as a mediator of inflammation-induced fibrosis after myocardial infarction

Extracellular matrix protein-1 as a mediator of inflammation-induced fibrosis after myocardial infarction

Irreversible fibrosis is a hallmark of myocardial infarction (MI) and heart failure. Extracellular matrix protein-1 (ECM-1) is up-regulated in these hearts, localized to fibrotic, inflammatory, and perivascular areas. ECM-1 originates predominantly from fibroblasts, macrophages, and pericytes/vascul...

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Bibliographic Details
Main Authors: Hardy, SA, Liesinger, L, Patrick, R, Poettler, M, Rech, L, Gindlhuber, J, Mabotuwana, NS, Ashour, D, Stangl, V, Bigland, M, Murtha, LA, Starkey, MR, Scherr, D, Hansbro, PM, Hoefler, G, Ramos, G, Cochain, C, Harvey, RP, Birner-Gruenberger, R, Boyle, AJ, Rainer, PP
Format: Journal article
Language:English
Published: Elsevier 2023

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