IL-21 induces death of marginal zone B cells during chronic inflammation.

Interleukin-2 (IL-2) and IL-21 share activities in the control of T- and B-cell maturation, proliferation, function, and survival. However, opposing roles for IL-2 and IL-21 have been reported in the development of regulatory T cells. To dissect unique, redundant, and opposing activities of IL-2 and...

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Bibliographic Details
Main Authors: Tortola, L, Yadava, K, Bachmann, M, Müller, C, Kisielow, J, Kopf, M
Format: Journal article
Language:English
Published: 2010