Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans.

The perforated whole-cell configuration of the patch-clamp technique was applied to functionally identified beta-cells in intact mouse pancreatic islets to study the extent of cell coupling between adjacent beta-cells. Using a combination of current- and voltage-clamp recordings, the total gap junct...

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Bibliographic Details
Main Authors: Zhang, Q, Galvanovskis, J, Abdulkader, F, Partridge, C, Göpel, S, Eliasson, L, Rorsman, P
Format: Journal article
Language:English
Published: 2008