Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen.

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen.

Monosomy of the human chromosome 6p terminal region results in a variety of congenital malformations that include brain, craniofacial, and organogenesis abnormalities. To examine the genetic basis of these phenotypes, we have carried out an unbiased functional analysis of the syntenic region of the...

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Váldodahkkit: Bogani, D, Willoughby, C, Davies, J, Kaur, K, Mirza, G, Paudyal, A, Haines, H, McKeone, R, Cadman, M, Pieles, G, Schneider, J, Bhattacharya, S, Hardy, A, Nolan, P, Tripodis, N, Depew, M, Chandrasekara, R, Duncan, G, Sharpe, P, Greenfield, A, Denny, P, Brown, S, Ragoussis, J, Arkell, R
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2005

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