Modulators of MHC class I-related protein 1-mediated antigen presentation

<p>The monomorphic MHC class I-related protein 1 (MR1) presents bacterial metabolites to mucosal-associated invariant T (MAIT) cells, an innate-like subset of T lymphocytes. The known MAIT-activating MR1 ligands are intermediates of riboflavin synthesis, a pathway specific to certain fungi and...

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Bibliographic Details
Main Author: Kulicke, CA
Other Authors: Cerundolo, V
Format: Thesis
Language:English
Published: 2018
Subjects: