Modulators of MHC class I-related protein 1-mediated antigen presentation
<p>The monomorphic MHC class I-related protein 1 (MR1) presents bacterial metabolites to mucosal-associated invariant T (MAIT) cells, an innate-like subset of T lymphocytes. The known MAIT-activating MR1 ligands are intermediates of riboflavin synthesis, a pathway specific to certain fungi and...
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Format: | Thesis |
Language: | English |
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2018
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